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Port 80 (Web) is open. Chan, laminin, collagen (type I, II, III, IV), proteoglycans Control of vascular tonus NO, prostacyclin (PGI2), prostaglandin E2 (PGE2), angiotensin-converting enzyme (ACE), thromboxane (TXA2), leukotrienes, endothelin-1 Control of cell proliferation Platelet-derived growth factor (PDGF), endothelial-derived growth factor (EDGF), fibroblast growth factor (FGF), insulin-like growth factor-1 (IGF-1), transforming growth factor-β (TGF-β), granulocyte-monocyte-colony stimulating factor (GM-CSF) Control of coagulation Von Willebrand factor (vWF), thromboplastin, platelet activating factor (PAF), plasminogen activator inhibitor 1 and 2 (PAI-1 and PAI-2), high molecular weight kininogen (HMWK), thombomodulin, antithrombin III, heparan sulfate, adenosine diphosphatase, tissue plasminogen activator, protein C Control of inflammatory processes and immunological function Interleukins-1, -6, -8, leukotrienes B4, C4, D4, E4, cell adhesion molecules (CAM), major histocompatibility complex II (MHC II) Fig.

Both of these techniques readily destroy the passive tension of muscle fibers in proportion to the degradation of the high-molecular-weight titin (Funatsu et al. This free-energy input is sufficient to generate a 66-fold concentration gradient of an uncharged molecule such as glucose. Research shows it costs six times more to attract a new customer than to retain existing customers and small increases in retention rates can result in disproportionate increases in profitability.

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